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REVIEW ARTICLE
Year : 2016  |  Volume : 3  |  Issue : 1  |  Page : 3-7

Molecular mechanisms of insulin signaling


1 Department of Human Anatomy, Faculty of Human Medicine, Ahmadu Bello University, Zaria-Kaduna State, Nigeria
2 Department of Veterinary Pathology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria-Kaduna State, Nigeria
3 Department of Chemical Pathology, Ahmadu Bello University, Zaria-Kaduna State, Nigeria
4 Department of Biochemistry, Ahmadu Bello University, Zaria-Kaduna State, Nigeria
5 Department of Integrated Science (Biology), College of Education, Minna, Niger State, Nigeria

Correspondence Address:
I A Iliya
Department of Human Anatomy, Ahmadu Bello University, Zaria, Kaduna State
Nigeria
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DOI: 10.4103/2384-5147.176267

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Insulin signaling pathway is an important biochemical pathway that affects glucose homeostasis in the body. The pathway can be influenced by a variety of factors ranging from fed-fasting states, stress levels, diseases and even hormones. The pathway is a signal transduction pathway that comprises of trigger mechanisms which serve as signals throughout insulin targeted cells for the purpose of metabolic actions (glucose homeostasis) as well as mitogenic actions in the body. In pathological conditions, the signal-flow in this pathway can get disrupted resulting in serious metabolic and mitogenic disturbances in the body.


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