Endometrial hyperplasia: A-2 decade retrospective analysis of histopathological pattern at a university teaching hospital in Northern Nigeria
Idris U Takai MBBS, MHPM, FCAI, FMCOG 1, Mohammed Bukar2, Ahmed A Mayun3, Emmanuel A Ugwa4, Bala M Audu2, Aisha Abdurrahman1
1 Department of Obstetrics and Gynaecology, Bayero University/Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria
2 Department of Obstetrics and Gynaecology, University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria
3 Department of Histopathology, University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria
4 Department of Obstetrics and Gynaecology, Federal Medical Centre, Birnin Kudu, Jigawa State, Nigeria
Idris U Takai
Department of Obstetrics and Gynaecology, Bayero University Kano/Aminu Kano Teaching Hospital, Kano PMB 3452, Kano State
Source of Support: None, Conflict of Interest: None
Background: Endometrial hyperplasia (EH) produces a continuum of lesions that may be a precursor to the development of endometrial cancer, but the risk of which depends on the type of hyperplasia.
Objective: To determine the prevalence and histopathological pattern of EH at the University of Maiduguri Teaching Hospital (UMTH), Maiduguri.
Materials and Methods: This was a 20-year retrospective review of all endometrial biopsies of patients diagnosed with EH in the histopathology department of the UMTH, Maiduguri, from January 1989 to December 2008 inclusive.
Results: A total of 862 endometrial biopsies were reviewed during the study period. Out of this, 541 biopsies were EH, giving a proportion of 62.3%. The age ranged from 10 to 79 years with a mean of 32.5 ± SD 10.4 years. Most of the patients (79.7%) were in their 3rd decade. The results showed that simple EH was the leading histopathological type accounting for 83.2% (450/541) of the cases. Complex EH was responsible for 14.8% (80/541) of cases, while atypical EH was found in only 11/541 (2.0%).
Conclusion: This study has shown that EH is very common among reproductive age women exposing them to high risk of endometrial cancers; therefore, close follow-up and definitive management are highly recommended.